Denamine
Antihistaminic
Denamine
Antihistaminic
Description
Denamine (Chlorpheniramine Maleate) is an alkylamine antihistamine. It is one of the most potent of the H1-blocking agents and is generally effective in relatively low doses. Denamine is not so prone to produce drowsiness and is among the most suitable agent for daytime use also. Denamine is readily absorbed from the gastro-intestinal tract, metabolized in the liver and excreted usually mainly as metabolites in the urine.
- AVAILABILITY: AVAILABLE
Composition
Denamine Tablet: Each tablet contains Chlorpheniramine Maleate Bp 4 mg.
Denamine Syrup: Each 5 ml syrup contains Chlorpheniramine Maleate BP 2 mg.
Indication
Mainly in allergic conditions including urticaria, sensitivity reactions, angioneurotic edema, seasonal hay fever, vasomotor rhinitis, cough, common cold, motion sickness, drug rash, allergic dermatitis, allergic asthma etc.
Dosage And Administration
Adults: 4 mg 3-4 times daily.
Children: up to 1 year: 1 mg twice daily.
1-5 years: 1-2 mg three times daily.
6-12 years: 2-4 mg 3-4 times daily.
Or, as directed by the physician.
Side Effects
Drowsiness, dizziness, headache, psychomotor impairment, urinary retention, dry mouth, blurred vision and gastrointestinal disturbances, paradoxical stimulation may rarely occur, especially in high dosage or in children.
Precautions
The ability to drive or operate machinery may be impaired.
Contraindication
There is no definite contraindication to therapy. It should be used with caution in epilepsy, prostatic hypertrophy, glaucoma and hepatic disease.
Pharmaceutical precaution
Store in a cool below 30C , dry place and protect from light. Keep out of reach of children.
Packing
Denamine Tablet: Box containing 50 x 10 tablets in blister pack.
Denamine Syrup: Amber glass bottle containing 60 ml syrup.